MIADERM Cancer Radiation Treatment Therapy

Miaderm Radiation Relief
Prevention of Radiation Dermatitis & Advanced Healing For Skin Damage Resulting From Radiation Therapy

MIADERM Cancer Radiation Treatment Therapy
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  Heal and Soothe Skin Problems from Radiation
ALOE VERA, also known as the medicinal aloe, is a species of succulent plant that probably originated in Northern Africa, the Canary islands and Cape Verde. Aloe vera grows in arid climates and is widely distributed in Africa and other arid areas. HYALURONATE ia our secret ingredient. Call us if you would like to mknow what it is! CALENDULA is a genus of about 12-20 species of annual or perennial herbaceous plants in the daisy family Asteraceae, native to the area from Macaronesia east through the Mediterranean region to Iran. MIADERM Cancer Radiation Treatment Therapy
  CALENDULA (>4%)   HYALURONATE (>4%)   ALOE VERA (>4%)  
MIADERM Cancer Radiation Treatment Therapy
In a prospective, randomized study of 254 radiation patients, topical, application of 4% calendula ointment resulted in far fewer occurrences of Grade 2 of higher clematitis than occurred in the group using Biafine (trilamine). Calendula users also experienced less radiation induced pain and fewer breaks in treatment.
(Pommier P.et al. J Clinical Oncol 2004; 22:447-1453)
MIADERM Cancer Radiation Treatment Therapy
In a randomized double-blind placebo-controlled study of 134 radiation patients, 0.2% hyaluronate cream was shown to significantly reduce the incidence of high-grade skin reactions, delay their onset & reduce their severity. The study also noted hyaluonate's association with faster skin recovery times.
(Ligouri V. et al, Radioth Oncol. 1997; 2:155-161)
MIADERM Cancer Radiation Treatment Therapy
In a prospective, randomized and blinded study, patients who applied aloe vera after applying a mild soap solution experienced initial skin irritation two weeks later than those who used the soap but not the aloe. The study noted that this finding suggests aloe vera may have a proactive effect.
(Olsen DL, et al. Oncol Nurs forum.
2001; 28:543-247)
MIADERM Cancer Radiation Treatment Therapy

One of the most uncomfortable side effects of radiation therapy is the skin reaction in the area being treated. Similar to a sunburn the skin may react with a mild to moderate pink color, or redness accompanied by itching, burning, soreness, and peeling. The effects of radiation on the skin are the most common side effects of radiation treatment, with up to 95% of patients experiencing an adverse skin reaction. One of the most significant problems associated with radiation dermatitis (burns) is that it can force interruptions in treatment, which have been proven to increase the risk of the cancer recurring.

Miaderm was developed by radiation oncologists specifically to minimize patients' skin-related side effects and ensure the effectiveness of their treatment. The goal was to create a lotion using an evidence based, scientific approach, with ingredients clinically proven to help:

  • reduce radiations effects on the skin
  • soothe and restore radiation-damaged skin
  • reduce or eliminate breaks in radiation treatment

Miaderm Radiation Relief lotion is a water-based lotion formulated with ingredients that are supported by scientific studies. The key ingredients of calendula, hyaluronate (hyaluronic acid), and aloe vera have been clinically proven to be effective in phase III prospective randomized trials published in peer reviewed scientific journals. The sole purpose of Miaderm is to help decrease the skin effects that patients experience in  being treated with radiation therapy.

Calendula (1) when compared to Biafine (trolamine) was shown to decrease the incidence of grade 2 or higher radiation dermatitis as well as reduce the incidence of treatment breaks. The study was a phase III prospective clinical trial published in the Journal of Clinical Oncology. A treatment break occurs when the skin is so damaged that radiation has to stop temporarily to allow for wound healing. Hyaluronate (2) when compared to a placebo cream was also shown to reduce the incidence of high grade radiation skin reactions, delay their onset, and reduce their severity. Earlier recovery was also seen in this phase three prospective trial, published in the journal Radiotherapy Oncology. There have been many studies looking at aloe vera effectiveness in treating and preventing radiation dermatitis. A phase III clinical study published in Oncology Nursing Forum showed that compared to mild soap alone, aloe vera (3) can delay the occurrence of radiation dermatitis. Other studies looking at aloe vera and radiation skin effects have not shown a proven benefit. To our knowledge Miaderm Radiation Relief is the only radiation therapy lotion formulated with greater than 4% concentrations of calendula, hyaluronate, and aloe vera.

To get the full benefit of Miaderm Radiation Relief should be started at the initiation of radiation therapy and continued for two weeks following the completion of treatment. Miaderm Radiation Relief lotion is unconditionally guaranteed.

(1) Pommier P, Gomez F, Sunyach MP, et al: Phase III randomized trial of calendula officinalis compared with trolamine for the prevention of acute dermatitis during irradiation for breast cancer. Journal of Clinical Oncology 22:1447-1453, 2004
(2) Liguori V, Guillemin C, Pesce GF, et al: Double-blind, randomized clinical study comparing hyaluronic acid cream to placebo in patients treated with radiotherapy. Radiotherapy Oncology 42:155–161, 1997
(3) Olsen DL, Raub W, Bradley C, et al: The effect of aloe vera gel versus mild soap alone in preventing skin reactions in patients undergoing radiation therapy. Oncology Nursing Forum 28:543-547, 2001

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