The science behind Miaderm’s evidence-based formulation.

scientific basis

Treating patients who have cancer is a crusade–to save lives, or to prolong them and give patients their best possible quality of life.

In radiation oncology, our role in this endeavor is to shrink tumors and kill cancer cells, and to do it despite the treatment itself often causing its own interruption. This makes avoiding or reducing radiation dermatitis an important part of the mission.

As radiation oncologists, we decided to take this challenge head-on to benefit not just our own patients but yours, as well. Looking at the problem as physicians, we followed the evidence.

Petrolatum provides no clear benefit.

While petroleum-based topical agents like Aquaphor are commonly recommended and used, studies have shown that they provide no clear benefit in the prevention or management of toxicity to the skin.

In a small study of breast-cancer patients who received chest wall irradiation, petrolatum gel showed no significant benefit over those patients who had received no topical treatment.1 In a larger Phase III study of women undergoing radiation treatment of the breast, petroleum-based topical treatment demonstrated no benefit as a prophylactic agent for radiation-induced skin toxicity.2

Evidence shows that aqueous cream does help.

In a Phase III study of 225 breast-cancer patients, those women who applied a topical aqueous cream throughout radiation treatment and for two weeks afterward experienced much less dry desquamation (dryness, scaling and itchiness) than those who used aloe vera.3 The researchers concluded that aqueous cream was useful in reducing both dry desquamation and pain associated with radiation treatment.3

Miaderm: Scientifically formulated to protect the skin and avoid treatment breaks.

Using aquous cream as its base, Miaderm Radiation Relief Lotion also contains other evidence-based ingredients shown to reduce the occurrence and severity of radiation dermatitis, including:


In a study of radiation therapy patients, application of calendula ointment resulted in far fewer occurrences of dermatitis than in the group using a traditional substance.4 Calendula users also experienced less radiation-induced pain and fewer breaks in treatment.4


In another study of radiation therapy patients, hyaluronate cream significantly reduced the incidence of high-grade skin reactions, delayed their onset and reduced their severity.5 The study also noted hyaluronate’s association with faster recovery from skin symptoms.5

Aloe Vera

In a third study, patients who applied aloe vera after applying a mild soap solution experienced initial skin irritation two weeks later than those who used the soap but not the aloe.6 The study noted that this suggests aloe vera may have a protective effect.6

To learn more about the evidence behind Miaderm’s formula and effectiveness, download our White Paper.

To order samples of Miaderm Radiation Relief products, please call 1-877-642-7727, ext. 103(NOTE: Samples are not intended or sized for clinical use.)

For wholesale pricing or orders, please call 1-877-642-7727, ext. 103 or contact us via our online form.

Patients can purchase Miaderm in the clinically appropriate size through our online store, at any of hundreds of pharmacies throughout North America, or from a variety of major online retailers.

1. Omidvari S, et al. Indian J Dermatol Venereol Leprol. 2007; 73(3):209
2. Fisher J, et al. Int J Radiat Oncol Biol Phys. 2000; 48:1307-1
3. Heggie S, et al. Cancer Nurs. 2002; 25(6):442-51
4. Pommier P, et al. J Clinical Oncol. 2004; 22:1447-1453
5. Ligouri V, et al. Radioth Oncol. 1997; 2:155-161
6. Olsen DL, et al. Oncol Nurs Forum. 2001; 28:543-247